RDR03871
Based on 1 Customer Validation
RDR03871 (compound 2) is a potent dual MDM2/MDM4 inhibitor with IC50 values of 35.4 nM and 10.4 nM for MDM2-p53 and MDM4-p53, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.00%
- No. CAS: 286008-51-3
- Fòrmula: C18H16ClF3N6
- Peso molecular:408.81
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
-
HY-15676
IdasanutlinMDM2 Inhibitor -
HY-112780
UC2288P21 Attenuator -
HY-12296
NavtemadlinMDM2-p53 Interaction Inhibitor -
HY-14714
NSC-207895p53 Activator -
HY-110182
SP-141MDM2 Inhibitor -
HY-10959
RG7112MDM2 Antagonist -
HY-128784
PK11007Anti-p53 Agent -
HY-16664
SJ-172550MDM-2/p53 MDM2 Inhibitor -
HY-16271
Kevetrin hydrochloridep53 Activator -
HY-15335
Nutlin-3bMDM-2/p53 MDM2 Inhibitor -
HY-15954
NVP-CGM097MDM2 Inhibitor -
HY-50696
Nutlin-3p53-MDM2 Inhibitor
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BTI-TN-5B1-4 | IC50 |
>100 μM
Compound: 35
|
Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroanilide as substrate after 20 mins by spectrophotometric analysis in presence of Bacillus coagulans GST-tagge
Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroanilide as substrate after 20 mins by spectrophotometric analysis in presence of Bacillus coagulans GST-tagge
|
[PMID: 23507151] |
Chemical Information
-
No. CAS 286008-51-3
-
Appearance Solid
-
Peso molecular 408.81
-
Fòrmula C18H16ClF3N6
-
Color White to off-white
-
SMILES
FC(F)(F)C1=CC=CC(NCCNC2=NC(C3=NC=CC=C3)=NC(C)=C2Cl)=N1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
-
Ficha de datos (265 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RDR03871 Related Classifications
HY-123544 Related Classifications
Powered by Bioz