2930378-91-7
2930378-91-7
Chemical Structure
GAK inhibitor 49 hydrochloride
- CAS No.: 2930378-91-7
- Formula:C20H23ClN2O5
- Molecular Weight:406.86
IUPAC Name: 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine hydrochloride
InChIKey: LOOMZTXOCDWFDB-UHFFFAOYSA-N
SMILES: COC1=C(OC)C(OC)=CC(NC2=CC=NC3=CC(OC)=C(OC)C=C23)=C1.[H]Cl
Biological Activity: GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GAK inhibitor 49 hydrochloride | 99.52% | GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-124793GAK inhibitor 49 -
Similarity Score 0.73
HY-169789PKN3-IN-1 -
Similarity Score 0.73
HY-122186SGC-GAK-1 -
Similarity Score 0.70
HY-Z1053Cabozantinib impurity 8 -
Similarity Score 0.66
HY-114189AGW284543 hydrochloride -
Similarity Score 0.65
HY-175300AChE-IN-92 -
Similarity Score 0.65
HY-114189GW284543 -
Similarity Score 0.64
HY-113892Leniquinsin -
Similarity Score 0.59
HY-146366Tubulin inhibitor 26 -
Explore the MedChemAI to find more analogs
