2941268-67-1
2941268-67-1
Chemical Structure
PPZ-A10
- CAS No.: 2941268-67-1
- Formula:C56H114N6O2
- Molecular Weight:903.54
InChIKey: PXNLDSAGMDIEAT-UHFFFAOYSA-N
SMILES: O=C(CCN(CCCCCCCCCC)CCCCCCCCCC)NCCCN1CCN(CCCNC(CCN(CCCCCCCCCC)CCCCCCCCCC)=O)CC1
Biological Activity: PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors[1][2].
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PPZ-A10 | 99.90% | PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors. | ||||||||||||||||||||
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References
- [1]. Ni H, et al. Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo. Nat Commun. 2022;13(1):4766. [Content Brief]
- [2]. Subhan MA, et al. Biopolymer-Based Nanosystems for siRNA Drug Delivery to Solid Tumors including Breast Cancer. Pharmaceutics. 2023 Jan 1;15(1):153. [Content Brief]
Keywords
