3000549-26-5

OICR-8268 Chemical Structure
3000549-26-5

Chemical Structure

OICR-8268

  • CAS No.: 3000549-26-5
  • Formula:C19H14Cl2F2N4O2
  • Molecular Weight:439.24

IUPAC Name: (S)-N-(3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl)-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide

InChIKey: IPDMIUDPUBUHSU-INIZCTEOSA-N

SMILES: O=C(C1=CNN=C1C2=CC=C(Cl)C=C2F)N[C@H](C3=CC=C(F)C(Cl)=C3)CC(N)=O

Biological Activity: OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-149935
OICR-8268 99.23% OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs.
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