3000549-26-5

OICR-8268 Chemical Structure
3000549-26-5

Chemical Structure

OICR-8268

  • CAS No.: 3000549-26-5
  • Formula:C19H14Cl2F2N4O2
  • Molecular Weight:439.24

IUPAC Name: (S)-N-(3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl)-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide

InChIKey: IPDMIUDPUBUHSU-INIZCTEOSA-N

SMILES: O=C(C1=CNN=C1C2=CC=C(Cl)C=C2F)N[C@H](C3=CC=C(F)C(Cl)=C3)CC(N)=O

Biological Activity: OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-149935
OICR-8268 99.23% OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References