3000549-26-5
3000549-26-5
Chemical Structure
OICR-8268
- CAS No.: 3000549-26-5
- Formula:C19H14Cl2F2N4O2
- Molecular Weight:439.24
IUPAC Name: (S)-N-(3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl)-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide
InChIKey: IPDMIUDPUBUHSU-INIZCTEOSA-N
SMILES: O=C(C1=CNN=C1C2=CC=C(Cl)C=C2F)N[C@H](C3=CC=C(F)C(Cl)=C3)CC(N)=O
Biological Activity: OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
OICR-8268 | 99.23% | OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.52
HY-121280ERK2-IN-4 -
Similarity Score 0.51
HY-169152DCAF1 ligand 1 -
Similarity Score 0.47
HY-10797CJ-42794 -
Similarity Score 0.46
HY-122168AAT-008 -
Similarity Score 0.46
HY-111449BAY-218 -
Similarity Score 0.46
HY-136244PF-06952229 -
Similarity Score 0.45
HY-126076VPC-80051 racemate -
Similarity Score 0.45
HY-126076AVPC-80051 -
Similarity Score 0.45
HY-135237DB04760 analog 1 -
Explore the MedChemAI to find more analogs
