3031765-75-7
3031765-75-7
Chemical Structure
ART615
- CAS No.: 3031765-75-7
- Formula:C21H21F3N4O2
- Molecular Weight:418.41
IUPAC Name: (2R,4R)-1-(3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-4-hydroxy-N-methyl-N-(m-tolyl)pyrrolidine-2-carboxamide
InChIKey: FAQDVYGMYVIYHD-CRAIPNDOSA-N
SMILES: O=C([C@@H]1N(C2=NC(C)=CC(C(F)(F)F)=C2C#N)C[C@H](O)C1)N(C)C3=CC=CC(C)=C3
Biological Activity: ART615 is the related isomer of ART558. ART615, the inactive of ART558, elicits <10% Polθ inhibition at 12 µM, thus serving as a control for ART558 (IC50=7.9 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ART615 | 98.60% | ART615 is the related isomer of ART558. ART615, the inactive of ART558, elicits <10% Polθ inhibition at 12 µM, thus serving as a control for ART558 (IC50=7.9 nM). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-141520GART558 (GMP) -
Similarity Score 0.61
HY-163816Antiproliferative agent-53-d3 -
Similarity Score 0.54
HY-139289ART812 -
Similarity Score 0.51
HY-208737KHK-IN-8 -
Similarity Score 0.50
HY-139289SART899 -
Similarity Score 0.49
HY-159078PolQi1 -
Similarity Score 0.48
HY-139593SPolθ-IN-1-d3 -
Similarity Score 0.47
HY-153755ART6043 -
Similarity Score 0.46
HY-180410YM-1758735 -
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