3033480-77-9
3033480-77-9
Chemical Structure
USP1-IN-8
- CAS No.: 3033480-77-9
- Formula:C29H24D3F4N7O2
- Molecular Weight:584.58
InChIKey: ZIBZASWCYUPCFJ-HPRDVNIFSA-N
SMILES: O=C1N(CC2=CC=C(C3=NC(C(F)(F)F)=CN3C(C)C)C=C2)C4=C(F)C(C5=C(OC)N=CN=C5C6CC6)=NC=C4N1C([2H])([2H])[2H]
Biological Activity: USP1-IN-8 (Compound 16) is an inhibitor for ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, with IC50 ≤50 nM. USP1-IN-8 inhibits proliferation of MDA-MB-436 with IC50 ≤50 nM[1].
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USP1-IN-8 | USP1-IN-8 (Compound 16) is an inhibitor for ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, with IC50 ≤50 nM. USP1-IN-8 inhibits proliferation of MDA-MB-436 with IC50 ≤50 nM. | |||||||||||||||||||||
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References
Keywords
