3033846-10-2
3033846-10-2
Chemical Structure
PF-07899895
- CAS No.: 3033846-10-2
- Formula:C23H23N5OS
- Molecular Weight:417.53
InChIKey: LTQKUGJNXFIXKC-UHFFFAOYSA-N
SMILES: N#CC1=CC=CC2=NC=C(N12)C3=CC(SC)=C(C#N)C(OCC4(CCCCC4)N)=C3
Biological Activity: PF-07899895 (Compound 34) is a SIK inhibitor, with IC50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1, SIK2, and SIK3, respectively. PF-07899895 modulates the anti-inflammatory cytokine IL-10 in immune cells. PF-07899895 is applicable to research related to inflammatory diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-07899895 | 98.83% | PF-07899895 (Compound 34) is a SIK inhibitor, with IC50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1, SIK2, and SIK3, respectively. PF-07899895 modulates the anti-inflammatory cytokine IL-10 in immune cells. PF-07899895 is applicable to research related to inflammatory diseases. | ||||||||||||||||||||
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References
Keywords
