1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK

GLPG0634 analog 

Cat. No.: HY-13961 Purity: 98.00%
Handling Instructions

GLPG0634 (analog) (compound176)is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents.

For research use only. We do not sell to patients.

GLPG0634 analog Chemical Structure

GLPG0634 analog Chemical Structure

CAS No. : 1206101-20-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 217 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
2 mg USD 144 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 240 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 420 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 1320 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Other Forms of GLPG0634 analog:

View All JAK Isoform Specific Products:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

GLPG0634 (analog) (compound176)is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents.

IC50 & Target[3]

JAK3

<100 nM (IC50)

Tyk2

<100 nM (IC50)

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.4365 mL 12.1823 mL 24.3647 mL
5 mM 0.4873 mL 2.4365 mL 4.8729 mL
10 mM 0.2436 mL 1.2182 mL 2.4365 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

410.43

Formula

C₂₃H₁₈N₆O₂

CAS No.

1206101-20-3

SMILES

O=C(C1CC1)NC2=NN3C(C4=CC=C(OCC5=CC=C(C#N)N=C5)C=C4)=CC=CC3=N2

Storage

4°C, protect from light, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 53 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
GLPG0634 analog
Cat. No.:
HY-13961
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