3034411-38-3
3034411-38-3
Chemical Structure
ZNL-05-044
- CAS No.: 3034411-38-3
- Formula:C21H22Cl2N6OS
- Molecular Weight:477.41
InChIKey: LHMJTCJXGOQGEX-UHFFFAOYSA-N
SMILES: CC1=NC(N2CCN(C)CC2)=CC=C1NC3=NC(N)=C(C(C4=C(Cl)C=CC=C4Cl)=O)S3
Biological Activity: ZNL-05-044 is a CDK11 inhibitor with an IC50s of 0.23 μM and 0.27 μM against CDK11A and CDK11B, respectively (NanoBRET assay). ZNL-05-044 leads to G2/M cell cycle arrest and impairs RNA splicing[1].
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ZNL-05-044 | 99.11% | ZNL-05-044 is a CDK11 inhibitor with an IC50s of 0.23 μM and 0.27 μM against CDK11A and CDK11B, respectively (NanoBRET assay). ZNL-05-044 leads to G2/M cell cycle arrest and impairs RNA splicing. | ||||||||||||||||||||
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References
Keywords
