3036155-26-4
Chemical Structure
PROTAC SOS1 degrader-7
- CAS No.: 3036155-26-4
- Formula:C51H64F2N10O4
- Molecular Weight:919.12
InChIKey: GFCVCRNMILTDSA-UUWRZZSWSA-N
SMILES: CC1=NN=C(C2=C1C=NC(N3CCN(CC3)C(C4CCN(CC4)CC5CCC6(CCN(CC6)C(C7=CC(N8CCC(NC8=O)=O)=C(C=C7)C)=O)CC5)=O)=C2)N[C@@H](C9=CC=CC(C(F)F)=C9C)C
Biological Activity: PROTAC SOS1 degrader-7 (Example 15) is a PROTAC degrader that targets SOS1 protein degradation by recruiting cereblon. PROTAC SOS1 degrader-7 is applicable to research on the SOS1-RAS signaling pathway and tumors associated with KRAS mutations[1].
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PROTAC SOS1 degrader-7 | PROTAC SOS1 degrader-7 (Example 15) is a PROTAC degrader that targets SOS1 protein degradation by recruiting cereblon. PROTAC SOS1 degrader-7 is applicable to research on the SOS1-RAS signaling pathway and tumors associated with KRAS mutations. | |||||||||||||||||||||
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Keywords