PROTAC SOS1 degrader-7
PROTAC SOS1 degrader-7 (Example 15) is a PROTAC degrader that targets SOS1 protein degradation by recruiting cereblon. PROTAC SOS1 degrader-7 is applicable to research on the SOS1-RAS signaling pathway and tumors associated with KRAS mutations.
(Pink: SOS1 ligand (HY-163583); Blue: Cereblon ligand (HY-W454906); Black: linker (HY-163584)).
For research use only. We do not sell to patients.
- CAS No.: 3036155-26-4
- Formula: C51H64F2N10O4
- Molecular Weight:919.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 3036155-26-4
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Molecular Weight 919.12
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Formula C51H64F2N10O4
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SMILES
CC1=NN=C(C2=C1C=NC(N3CCN(CC3)C(C4CCN(CC4)CC5CCC6(CCN(CC6)C(C7=CC(N8CCC(NC8=O)=O)=C(C=C7)C)=O)CC5)=O)=C2)N[C@@H](C9=CC=CC(C(F)F)=C9C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)