3036645-03-8
3036645-03-8
Chemical Structure
BC13
- CAS No.: 3036645-03-8
- Formula:C37H39N7O5
- Molecular Weight:661.75
InChIKey: GCDVHXYXNPHYTC-UHFFFAOYSA-N
SMILES: COC1=C2C(NC(C3=CC=C(C=C3)C(N4CC5(C4)CCN(CC5)C6=NC(N7C8CCCC8)=C(C=N6)C(C)=CC7=O)=O)=NC2=CC(OC)=C1)=O
Biological Activity: BC13 is a CDK6/BRD4 inhibitor with the IC50 values of 234 nM and 36 nM for CDK6 and BRD4, respectively. BC13 shows antiproliferative activity and induces cell apoptosis and DNA damage. BC13 increases in ROS levels[1].
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BC13 | BC13 is a CDK6/BRD4 inhibitor with the IC50 values of 234 nM and 36 nM for CDK6 and BRD4, respectively. BC13 shows antiproliferative activity and induces cell apoptosis and DNA damage. BC13 increases in ROS levels. | |||||||||||||||||||||
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References
Keywords
