3038446-91-9
3038446-91-9
Chemical Structure
SK2187
Synonym(s): JB301
- CAS No.: 3038446-91-9
- Formula:C45H49ClFN7O11S
- Molecular Weight:950.43
InChIKey: ROINLDWZNWCWJK-ZYIHSGTPSA-N
SMILES: O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(OCC(NCCOCCOCCOCCNC([C@@]4(CC[C@H](CC4)OC5=C(C(Cl)=CC=C5)F)CC6=CC=CC(NC7=NC=CS7)=N6)=O)=O)=C3C1=O
Biological Activity: SK2187 (JB301) is a selective AURKA PROTAC degrader. SK2187 induces targeted degradation of AURKA by recruiting the CRBN E3 ubiquitin ligase. SK2187 is applicable to research related to neuroblastoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SK2187 | 95.81% | SK2187 (JB301) is a selective AURKA PROTAC degrader. SK2187 induces targeted degradation of AURKA by recruiting the CRBN E3 ubiquitin ligase. SK2187 is applicable to research related to neuroblastoma. | ||||||||||||||||||||
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