3047792-52-6
3047792-52-6
Chemical Structure
JNK-1-IN-2
- CAS No.: 3047792-52-6
- Formula:C16H20BrN5O
- Molecular Weight:378.27
InChIKey: HSEASLMARZYTKL-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC=CC=C1NC2=NC(NCC(C)(C)C)=NC=C2Br
Biological Activity: JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor (IC50: 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC50s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun. JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis[1].
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JNK-1-IN-2 | JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor (IC50: 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC50s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun. JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis. | |||||||||||||||||||||
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References
Keywords
