JNK-1-IN-2
JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor (IC50: 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC50s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun. JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis.
For research use only. We do not sell to patients.
- CAS No.: 3047792-52-6
- Formula: C16H20BrN5O
- Molecular Weight:378.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
33.5 nM, 112.9 nM and 33.2 nM (JNK-1, JNK-2 and JNK-3)[1]
Chemical Information
-
CAS No. 3047792-52-6
-
Molecular Weight 378.27
-
Formula C16H20BrN5O
-
SMILES
O=C(N)C1=CC=CC=C1NC2=NC(NCC(C)(C)C)=NC=C2Br
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)