306-60-5
306-60-5
Chemical Structure
Agmatine
- CAS No.: 306-60-5
- Formula:C5H14N4
- Molecular Weight:130.19
IUPAC Name: 1-(4-aminobutyl)guanidine
InChIKey: QYPPJABKJHAVHS-UHFFFAOYSA-N
SMILES: NC(NCCCCN)=N
Biological Activity: Agmatine is an orally active analgesic that can cross the blood-brain barrier. Agmatine targets the 5-HT2A receptor, 5-HT3 receptor, α2-adrenergic receptor, and I1 imidazoline receptor. Agmatine produces dose-dependent analgesic effects in various pain models. Agmatine can be used in research related to visceral pain, neuropathic pain, and inflammatory pain[1][2].
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Agmatine | Agmatine is an orally active analgesic that can cross the blood-brain barrier. Agmatine targets the 5-HT2A receptor, 5-HT3 receptor, α2-adrenergic receptor, and I1 imidazoline receptor. Agmatine produces dose-dependent analgesic effects in various pain models. Agmatine can be used in research related to visceral pain, neuropathic pain, and inflammatory pain. | |||||||||||||||||||||
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References
- [1]. Nudelman N. Aromatic nucleophilic substitution in aprotic solvents using hydrogen-bonded biological amines. Kinetic studies and quantum chemical calculations[J]. Journal of Physical Organic Chemistry, 2015.
- [2]. Santos AR, et al. Mechanisms involved in the antinociception caused by agmatine in mice. Neuropharmacology. 2005;48(7):1021-1034. [Content Brief]
