31431-39-7
31431-39-7
Chemical Structure
Mebendazole
- CAS No.: 31431-39-7
- Formula:C16H13N3O3
- Molecular Weight:295.29
IUPAC Name: methyl (6-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate
InChIKey: OPXLLQIJSORQAM-UHFFFAOYSA-N
SMILES: O=C(OC)NC1=NC2=CC=C(C(C3=CC=CC=C3)=O)C=C2N1
Biological Activity: Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mebendazole | 99.78% | Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration. | ||||||||||||||||||||
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Mebendazole (Standard) | 99.49% | Mebendazole (Standard) is the analytical standard of Mebendazole. This product is intended for research and analytical applications. Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration. | ||||||||||||||||||||
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Mebendazole-d8 | Mebendazole-d8 is the deuterium labeled Mebendazole. Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor. | |||||||||||||||||||||
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Mebendazole-d3 | Mebendazole-d3 is the deuterium labeled Mebendazole. | |||||||||||||||||||||
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References
- [1]. Bai RY, et al. Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme. Neuro Oncol. 2011 Sep;13(9):974-82. [Content Brief]
- [2]. Larsen AR, et al. Repurposing the antihelmintic mebendazole as a hedgehog inhibitor. Mol Cancer Ther. 2015 Jan;14(1):3-13. [Content Brief]
- [3]. Erdinçler P, et al. The role of mebendazole in the surgical treatment of central nervous system hydatid disease. Br J Neurosurg. 1997 Apr;11(2):116-20. [Content Brief]
