32797-92-5
Chemical Structure
Glipentide
- CAS No.: 32797-92-5
- Formula:C22H27N3O5S
- Molecular Weight:445.53
IUPAC Name: N-(4-(N-(cyclopentylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide
InChIKey: NSJYMFYVNWVGON-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1OC)NCCC2=CC=C(C=C2)S(=O)(NC(NC3CCCC3)=O)=O
Biological Activity: Glipentide is a sulfonylurea receptor agonist. Glipentide increases the concentration of fructose-2,6-bisphosphate in rat hepatocytes and inhibits basal gluconeogenesis. Glipentide can reduce glycerol production in rat adipose tissue. Glipentide can be used in research on endocrine and metabolic diseases such as diabetes[1][2].
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Glipentide | Glipentide is a sulfonylurea receptor agonist. Glipentide increases the concentration of fructose-2,6-bisphosphate in rat hepatocytes and inhibits basal gluconeogenesis. Glipentide can reduce glycerol production in rat adipose tissue. Glipentide can be used in research on endocrine and metabolic diseases such as diabetes. | |||||||||||||||||||||
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- [1]. López-Alarcón L, et al. Glipentide and glucose metabolism in isolated rat hepatocytes. Biochem Pharmacol. 1988 Aug 15;37(16):3177-82. [Content Brief]
- [2]. Herrera E. Effects of sulfonylureas (tolbutamide, glipentide and glibenclamide) on in vitro glycerol metabolism in adipose tissue from rats. Life Sci. 1975 Feb 15;16(4):645-50. [Content Brief]
Keywords
