33178-86-8
33178-86-8
Chemical Structure
Alinidine
Synonym(s): St-567
- CAS No.: 33178-86-8
- Formula:C12H13Cl2N3
- Molecular Weight:270.16
IUPAC Name: N-allyl-N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
InChIKey: OXTYVEUAQHPPMV-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(Cl)=C1N(CC=C)C2=NCCN2
Biological Activity: Alinidine (St-567) is a specific bradycardic agent. Alinidine reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine shows antiischemic and antiarrhythmic effects[1][2].
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Alinidine | Alinidine (St-567) is a specific bradycardic agent. Alinidine reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine shows antiischemic and antiarrhythmic effects. | |||||||||||||||||||||
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References
- [1]. Snyders DJ, et al. Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Arch. 1987;410(1-2):83-91. [Content Brief]
- [2]. J L Challinor-Rogers, et al. Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. J Cardiovasc Pharmacol. 1997 Apr;29(4):499-507. [Content Brief]
