332108-65-3
Chemical Structure
ABMA
- CAS No.: 332108-65-3
- Formula:C18H24BrNO
- Molecular Weight:350.29
IUPAC Name: N-(5-bromo-2-methoxybenzyl)adamantan-1-amine
InChIKey: UCAHJECAHMOSHI-UHFFFAOYSA-N
SMILES: COC1=CC=C(Br)C=C1CNC2(C3)CC4CC3CC(C4)C2
Biological Activity: ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity[1][2].
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ABMA | 98.50% | ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity. | ||||||||||||||||||||
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- [1]. Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments. [Content Brief]
- [2]. Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10(8):1140-1147. [Content Brief]
Keywords
