Oxphaman
Oxphaman is a pea lipoxygenase inhibitor with an IC50 of 140 nM against pea lipoxygenase. Oxphaman inhibits protamine sulfate-induced degranulation of rat peritoneal mast cells.
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- CAS No.: 112851-89-5
- Formule: C17H21NO2
- Masse moléculaire:271.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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lipoxygenase 140 nM (IC50) |
Oxphaman (ZIMET 47/79) inhibits purified pea lipoxygenase activity with an IC50 of 1.4×10-4 mol/L[1].
Oxphaman (5 minutes prior to protamine sulfate activation) inhibits protamine sulfate-induced degranulation of peritoneal rat mast cells with an IC50 of 3.4×10-5 mol/L[1].
Oxphaman (2.5×10-4-5×10-4 mol/L; 5 minutes prior to Triton X-100 activation) weakly inhibits Triton X-100-induced degranulation of peritoneal rat mast cells, with 26.0% inhibition at 5×10-4 mol/L and 13.9% inhibition at 2.5×10-4 mol/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 112851-89-5
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Masse moléculaire 271.35
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Formule C17H21NO2
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SMILES
OC1=CC=C(C(/C=N/C23CC4CC(C3)CC(C2)C4)=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oxphaman Related Classifications
HY-183237 Related Classifications
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