333745-53-2
333745-53-2
Chemical Structure
LX2343
- CAS No.: 333745-53-2
- Formula:C22H19ClN2O6S
- Molecular Weight:474.91
IUPAC Name: N-(benzo[d][1,3]dioxol-5-yl)-2-(N-(5-chloro-2-methoxyphenyl)phenylsulfonamido)acetamide
InChIKey: ZGYSGIYKAVUVOR-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OCO2)C2=C1)CN(C3=CC(Cl)=CC=C3OC)S(=O)(C4=CC=CC=C4)=O
Biological Activity: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
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LX2343 | 99.77% | LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance. | ||||||||||||||||||||
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Keywords
