34042-85-8
34042-85-8
Chemical Structure
Sudoxicam
- CAS No.: 34042-85-8
- Formula:C13H11N3O4S2
- Molecular Weight:337.37
IUPAC Name: 4-hydroxy-2-methyl-N-(thiazol-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
InChIKey: SYCHUQUJURZQMO-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC=C12)=C(C(NC3=NC=CS3)=O)N(C)S2(=O)=O
Biological Activity: Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity[1][2][3].
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Sudoxicam | 99.96% | Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity. | ||||||||||||||||||||
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Sudoxicam (Standard) | ≥98% | Sudoxicam (Standard) is the analytical standard of Sudoxicam. This product is intended for research and analytical applications. Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity. | ||||||||||||||||||||
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References
- [1]. Obach RS, et al. In vitro metabolism and covalent binding of enol-carboxamide derivatives and anti-inflammatory agents sudoxicam and meloxicam: insights into the hepatotoxicity of sudoxicam. Chem Res Toxicol. 2008 Sep;21(9):1890-9. [Content Brief]
- [2]. Wiseman EH, et al. Anti-inflammatory and pharmacokinetic properties of sudoxicam N-(2-thiazolyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide. Biochem Pharmacol. 1972 Sep 1;21(17):2323-34. [Content Brief]
- [3]. Zhi-Yi Zhang. Sudoxicam. Handbook of Metabolic Pathways of Xenobiotics. September 2014.
Keywords
