3458-22-8
3458-22-8
Chemical Structure
Yoshi-864
Synonym(s): NSC-102627
- CAS. Nr.: 3458-22-8
- Formula:C8H20ClNO6S2
- Molecular Weight:325.83
IUPAC Name: azanediylbis(propane-3,1-diyl) dimethanesulfonate hydrochloride
InChIKey: YWCASUPWYFFUHE-UHFFFAOYSA-N
SMILES: CS(=O)(OCCCNCCCOS(C)(=O)=O)=O.[H]Cl
Biological Activity: Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor[1].
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Yoshi-864 | Yoshi-864 (NSC-102627) is an alkylsulfonate DNA crosslinker with anticancer activity. Yoshi-864 extends markedly the survival times of mice bearing L1210 leukemia or Ehrlich ascites carcinoma. Yoshi-864 also has a persistent reduction in ability to synthesize DNA in tumor cells from mice bearing the Ehrlich tumor. | |||||||||||||||||||||
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