346599-65-3
346599-65-3
Chemical Structure
D-69491 hydrochloride
- CAS No.: 346599-65-3
- Formula:C25H26Cl2FN7O3
- Molecular Weight:562.42
IUPAC Name: (Z)-5-((4-((3-chloro-4-fluorophenyl)amino)-6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-5-ylidene)methyl)-4-methyl-N-(2-morpholinoethyl)-1H-pyrrole-2-carboxamide hydrochloride
InChIKey: CLVDFRRQUCVMJY-PXJKFVASSA-N
SMILES: O=C(C1=CC(C)=C(/C=C(C2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2N4)\C4=O)N1)NCCN5CCOCC5.Cl
Biological Activity: D-69491 hydrochloride is a HER-2 tyrosine kinase inhibitor that reduces HER-2 phosphorylation, inhibits the proliferation of SKOV-3 cells, and has anticancer activity[1].
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D-69491 hydrochloride | D-69491 hydrochloride is a HER-2 tyrosine kinase inhibitor that reduces HER-2 phosphorylation, inhibits the proliferation of SKOV-3 cells, and has anticancer activity. | |||||||||||||||||||||
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References
Keywords
