350820-13-2
350820-13-2
Chemical Structure
Kynurenic acid-d5
Synonym(s): Quinurenic acid-d5
- CAS No.: 350820-13-2
- Formula:C10H2D5NO3
- Molecular Weight:194.20
IUPAC Name: 4-hydroxyquinoline-2-carboxylic-3,5,6,7,8-d5 acid
InChIKey: HCZHHEIFKROPDY-RALIUCGRSA-N
SMILES: OC1=C([2H])C(C(O)=O)=NC2=C1C([2H])=C([2H])C([2H])=C2[2H]
Biological Activity: Kynurenic acid-d5 is the deuterium labeled Kynurenic acid. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kynurenic acid-d5 | 99.85% | Kynurenic acid-d5 is the deuterium labeled Kynurenic acid. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. | ||||||||||||||||||||
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Kynurenic acid (Standard) | 98.87% | Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. | ||||||||||||||||||||
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Kynurenic acid | 99.93% | Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Wang J, et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006 Aug 4;281(31):22021-8. [Content Brief]
