351416-47-2
351416-47-2
Chemical Structure
Nemorosone
- CAS No.: 351416-47-2
- Formula:C33H42O4
- Molecular Weight:502.68
IUPAC Name: (1R,5S,7S)-5-benzoyl-4-hydroxy-6,6-dimethyl-1,3,7-tris(3-methylbut-2-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
InChIKey: NXZAENPZCAUREW-RFQWPUQQSA-N
SMILES: O=C(C1=CC=CC=C1)[C@@]23C([C@@](C(C(C/C=C(C)/C)=C2O)=O)(C[C@H](C/C=C(C)/C)C3(C)C)C/C=C(C)/C)=O
Biological Activity: Nemorosone is the main component of the floral resin of Clusia rosea. Nemorosone has an antiproliferative effect on cancer cells. Nemorosone induces apoptosis in HT-29 and LoVo cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nemorosone | 99.0% | Nemorosone is the main component of the floral resin of Clusia rosea. Nemorosone has an antiproliferative effect on cancer cells. Nemorosone induces apoptosis in HT-29 and LoVo cells. | ||||||||||||||||||||
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References
- [1]. Frión-Herrera Y, Gabbia D, Scaffidi M, et al. The Cuban Propolis Component Nemorosone Inhibits Proliferation and Metastatic Properties of Human Colorectal Cancer Cells. Int J Mol Sci. 2020;21(5):1827. Published 2020 Mar 6. [Content Brief]
- [2]. Wolf RJ, et al. In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. PLoS One. 2013;8(9):e74555. Published 2013 Sep 5. [Content Brief]
Keywords
