351862-32-3
351862-32-3
Chemical Structure
Sarizotan
Synonym(s): EMD 128130
- CAS No.: 351862-32-3
- Formula:C22H21FN2O
- Molecular Weight:348.41
IUPAC Name: (R)-1-(chroman-2-yl)-N-((5-(4-fluorophenyl)pyridin-3-yl)methyl)methanamine
InChIKey: HKFMQJUJWSFOLY-OAQYLSRUSA-N
SMILES: FC1=CC=C(C2=CN=CC(CNC[C@H]3CCC4=CC=CC=C4O3)=C2)C=C1
Biological Activity: Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sarizotan | 98.23% | Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively. | ||||||||||||||||||||
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Sarizotan (Standard) | ≥98% | Sarizotan (Standard) is the analytical standard of Sarizotan. This product is intended for research and analytical applications. Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-100820ASarizotan hydrochloride -
Similarity Score 0.97
HY-100820BSarizotan dihydrochloride -
Similarity Score 0.54
HY-105539EMD 86006 -
Similarity Score 0.54
HY-14782Adoprazine -
Similarity Score 0.53
HY-14782AAdoprazine hydrochloride -
Similarity Score 0.52
HY-150719AIMP2-DX2-IN-1 -
Similarity Score 0.51
HY-167631Desfluoro nebivolol -
Similarity Score 0.51
HY-145270ELOVL1-IN-2 -
Similarity Score 0.51
HY-101698Alniditan -
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