35225-13-9

Rifamycin AF-013 Chemical Structure
35225-13-9

Chemical Structure

Rifamycin AF-013

  • CAS No.: 35225-13-9
  • Formula:C46H64N2O13
  • Molecular Weight:853.01

InChIKey: DTEDDHSJILGOKQ-DYSHAYIOSA-N

SMILES: O=C(C)O[C@@H]1[C@@H]([C@H](/C=C/O[C@@]2(C)OC3=C(C4=C(C(/C=N/OCCCCCCCC)=C(C(O)=C4C(O)=C3C)NC(/C(C)=C/C=C/[C@@H]([C@@H]([C@H]([C@H]([C@H]1C)O)C)O)C)=O)O)C2=O)OC)C

Biological Activity: Rifamycin AF-013 is a derivative of Rifamycin (HY-B1907). Rifamycin AF-013 inhibits DNA polymerase γ by competing with dTTP and template primers for binding. Rifamycin AF-013 exhibits inhibitory activity against Rifampicin (HY-B0272)-resistant RNA polymerase. Rifamycin AF-013 inhibits non-polymerase enzymes including glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), and Alkaline phosphatase. Rifamycin AF-013 can be used in research related to Rifampicin-resistant bacterial infections and Ehrlich ascites tumors[1][2].

Cat. No. Product Name Purity Description Pricing
HY-131319 		Rifamycin AF-013 Rifamycin AF-013 is a derivative of Rifamycin (HY-B1907). Rifamycin AF-013 inhibits DNA polymerase γ by competing with dTTP and template primers for binding. Rifamycin AF-013 exhibits inhibitory activity against Rifampicin (HY-B0272)-resistant RNA polymerase. Rifamycin AF-013 inhibits non-polymerase enzymes including glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), and Alkaline phosphatase. Rifamycin AF-013 can be used in research related to Rifampicin-resistant bacterial infections and Ehrlich ascites tumors.
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