36386-71-7
Chemical Structure
MK-251
- CAS No.: 36386-71-7
- Formula:C17H17F4N
- Molecular Weight:311.32
InChIKey: YTXBIQSEDPVQBC-UHFFFAOYSA-N
SMILES: FC(C1=CC=CC=C1)(C(F)(C2=CC=C(C(C)(C)N)C=C2)F)F
Biological Activity: MK-251 is an orally active anti-arrhythmic agent. MK-251 prevents or modifies ventricular arrhythmias induced in dogs and baboons by tetrafluorethylbutylamine. MK-251 antagonizes the arrhythmias caused by Digoxin (HY-B1049) in cats. MK-251 at effective doses has little effect on basic cardiovascular parameters such as blood pressure, cardiac output, myocardial contractility and ventricular conduction, thus demonstrating its unique advantages[1].
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MK-251 | MK-251 is an orally active anti-arrhythmic agent. MK-251 prevents or modifies ventricular arrhythmias induced in dogs and baboons by tetrafluorethylbutylamine. MK-251 antagonizes the arrhythmias caused by Digoxin (HY-B1049) in cats. MK-251 at effective doses has little effect on basic cardiovascular parameters such as blood pressure, cardiac output, myocardial contractility and ventricular conduction, thus demonstrating its unique advantages. | |||||||||||||||||||||
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Keywords
