376640-41-4
376640-41-4
Chemical Structure
BVT 2733
- CAS No.: 376640-41-4
- Formula:C17H21ClN4O3S2
- Molecular Weight:428.96
IUPAC Name: 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide
InChIKey: YDPRNGAPPNPYQQ-UHFFFAOYSA-N
SMILES: ClC1=C(C)C(S(NC2=NC(CC(N3CCN(C)CC3)=O)=CS2)(=O)=O)=CC=C1
Biological Activity: BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BVT 2733 | 99.24% | BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
BVT 2733 (Standard) | ≥98% | BVT 2733 (Standard) is the analytical standard of BVT 2733. This product is intended for research and analytical applications. BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.99
HY-18054ABVT-2733 hydrochloride -
Similarity Score 0.75
HY-18055BVT-14225 -
Similarity Score 0.71
HY-18057BVT-3498 -
Similarity Score 0.47
HY-164567SID 125240931 -
Similarity Score 0.46
HY-W517275Sulfamethylthiazole -
Similarity Score 0.46
HY-101789Nav1.7-IN-3 -
Similarity Score 0.46
HY-15720BGlycyl H-1152 hydrochloride -
Similarity Score 0.46
HY-19055FK-613 -
Similarity Score 0.46
HY-12309011β-HSD1-IN-12 -
Explore the MedChemAI to find more analogs
