Glycyl H-1152 hydrochloride
Based on 1 Customer Validation
Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 913844-45-8
- Formula: C18H26Cl2N4O3S
- Molecular Weight:449.40
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Aurora Kinase Isoforms
More
Biological Activity
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ROCKII 11.8 nM (IC50) |
Aurora A 2.35 μM (IC50) |
CaMK II 2.57 μM (IC50) |
PKG 3.26 μM (IC50) |
Chemical Information
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CAS No. 913844-45-8
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Appearance Liquid
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Molecular Weight 449.40
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Formula C18H26Cl2N4O3S
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Color Colorless to light yellow
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SMILES
O=S(N1[C@@H](C)CN(C(CN)=O)CCC1)(C2=CC=CC3=C2C(C)=CN=C3)=O.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (272 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glycyl H-1152 hydrochloride Related Classifications
HY-15720B Related Classifications
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