379692-00-9
Chemical Structure
CP-664511
- CAS No.: 379692-00-9
- Formula:C28H34N4O6
- Molecular Weight:522.59
IUPAC Name: (S)-3-(3-(1-(2-(3-methoxy-4-(3-(o-tolyl)ureido)phenyl)acetamido)-3-methylbutyl)isoxazol-5-yl)propanoic acid
InChIKey: USEDUTJSKDZBGX-QHCPKHFHSA-N
SMILES: O=C(O)CCC1=CC([C@@H](NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C(OC)=C2)=O)CC(C)C)=NO1
Biological Activity: CP-664511 is an orally active and potent α4β1 integrin antagonist with anti-inflammatory effects (IC50=0.52 nM). CP-664511 inhibits the interaction between α4β1 and vascular cell adhesion molecule-1 (VCAM-1), significantly reducing eosinophil infiltration into lung tissue. CP-664511 is promising for research of asthma and allergic airway diseases[1].
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CP-664511 | CP-664511 is an orally active and potent α4β1 integrin antagonist with anti-inflammatory effects (IC50=0.52 nM). CP-664511 inhibits the interaction between α4β1 and vascular cell adhesion molecule-1 (VCAM-1), significantly reducing eosinophil infiltration into lung tissue. CP-664511 is promising for research of asthma and allergic airway diseases. | |||||||||||||||||||||
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