3930-20-9
3930-20-9
Chemical Structure
Sotalol
- CAS No.: 3930-20-9
- Formula:C12H20N2O3S
- Molecular Weight:272.36
IUPAC Name: N-(4-(1-hydroxy-2-(isopropylamino)ethyl)phenyl)methanesulfonamide
InChIKey: ZBMZVLHSJCTVON-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC=C(C(O)CNC(C)C)C=C1)=O
Biological Activity: Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3].
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Sotalol | Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent. | |||||||||||||||||||||
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References
- [1]. Marta Reyes-Corral, et al. Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines. J Pharmacol Exp Ther. 2019 Apr;369(1):152-162. [Content Brief]
- [2]. Xiaomei Li, et al. Pediatric Dosing of Intravenous Sotalol Based on Body Surface Area in Patients with Arrhythmia. Pediatr Cardiol. 2017 Oct;38(7):1450-1455. [Content Brief]
- [3]. Kinga K Borowicz-Reutt, et al. Sotalol does not interfere with the antielectroshock action of selected second-generation antiepileptic drugs in mice.Pharmacol Rep. 2021 Apr;73(2):516-524. [Content Brief]
Keywords
