39372-30-0
Chemical Structure
Candicidin D
Synonym(s): CndD
- CAS No.: 39372-30-0
- Formula:C59H84N2O18
- Molecular Weight:1109.30
IUPAC Name: (10R,12S,14S,18S,19S,20S,22R,23E,25E,27E,29E,31E,33Z,35E,37S,38R)-22-(((2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-38-((2S,4S,5S)-7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl)-10,12,14,18,20-pentahydroxy-37-methyl
InChIKey: OPGSFDUODIJJGF-KFTIXMKNSA-N
SMILES: C[C@H]1/C=C/C=C\C=C\C=C\C=C\C=C\C=C\[C@H](O[C@H]2[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O2)C[C@H](O)[C@H](C(O)=O)[C@@H](O)CC(C[C@@H](O)C[C@@H](O)C[C@@H](O)CC(CCCC(CC(O[C@]1([H])[C@H](C[C@@H]([C@@H](O)CC(C3=CC=C(N)C=C3)=O)C)C)=O)=O)=O)=O
Biological Activity: Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.
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Candicidin D | Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium. | |||||||||||||||||||||
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Keywords
