39455-18-0
Chemical Structure
Chondroitin sulfate A disodium
- CAS No.: 39455-18-0
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: (3S,6R)-6-(((2R,5R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-(sulfooxy)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
SMILES: O=C([C@@H]1C(O)[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](O[H])O[C@H](CO)[C@@H]2OS(=O)(O[Na])=O)O1)O[Na].[n]
Biological Activity: Chondroitin sulfate A disodium is a mucopolysaccharide extracted from animal cartilages such as porcine nasal cartilage, and serves as a major structural component of cartilage. Chondroitin sulfate A disodium is one of the specific receptors for the adhesion of Plasmodium falciparum-infected red blood cells in the microcirculation. Chondroitin sulfate A disodium can be used together with selenium to prepare nanoparticles for protecting cartilage against T‑2 toxin-induced damage. Chondroitin sulfate A disodium is abnormally highly expressed in ameloblastoma, and is particularly enriched in stellate reticulum-like tumor cells. Chondroitin sulfate A disodium can be applied to studies on Plasmodium infection mechanisms, cartilage protection and oral tumors[1][2][3].
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Chondroitin sulfate A disodium | Chondroitin sulfate A disodium is a mucopolysaccharide extracted from animal cartilages such as porcine nasal cartilage, and serves as a major structural component of cartilage. Chondroitin sulfate A disodium is one of the specific receptors for the adhesion of Plasmodium falciparum-infected red blood cells in the microcirculation. Chondroitin sulfate A disodium can be used together with selenium to prepare nanoparticles for protecting cartilage against T‑2 toxin-induced damage. Chondroitin sulfate A disodium is abnormally highly expressed in ameloblastoma, and is particularly enriched in stellate reticulum-like tumor cells. Chondroitin sulfate A disodium can be applied to studies on Plasmodium infection mechanisms, cartilage protection and oral tumors. | |||||||||||||||||||||
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- [1]. Deng H, et al. Chondroitin sulfate A-selenium nanoparticles protect chondrocytes from T-2 toxin-induced oxidative stress and mitochondrial dysfunction through activating autophagy by the SIRT1-AMPK-FOXO3 pathway. Ecotoxicol Environ Saf. 2025;303:118797. [Content Brief]
- [2]. Li X, et al. Potential involvement of chondroitin sulfate A in the pathogenesis of ameloblastoma. Acta Histochem. 2017;119(5):439-445. [Content Brief]
- [3]. Rogerson SJ, et al. Chondroitin sulfate A is a cell surface receptor for Plasmodium falciparum-infected erythrocytes. J Exp Med. 1995;182(1):15-20. [Content Brief]
Keywords
