400882-07-7
Chemical Structure
Cyflumetofen
- CAS No.: 400882-07-7
- Formula:C24H24F3NO4
- Molecular Weight:447.45
IUPAC Name: 2-methoxyethyl 2-(4-(tert-butyl)phenyl)-2-cyano-3-oxo-3-(2-(trifluoromethyl)phenyl)propanoate
InChIKey: AWSZRJQNBMEZOI-UHFFFAOYSA-N
SMILES: COCCOC(C(C(C1=C(C(F)(F)F)C=CC=C1)=O)(C2=CC=C(C(C)(C)C)C=C2)C#N)=O
Biological Activity: Cyflumetofen is a non-systemic acylacetonitrile Acaricide. Cyflumetofen interferes with the Wnt/β-catenin signaling pathway, induces Apoptosis, and reduces the level of tight junction proteins. Cyflumetofen upregulates the expression of Pink1, Parkin and Lrrk2 genes associated with the pathogenesis of Parkinson's disease in zebrafish larvae. Cyflumetofen induces developmental toxicity and oxidative stress in zebrafish larvae, damages neurons, reduces motor activity, alters brain tissue structure, and disrupts blood-brain barrier structure. Cyflumetofen exhibits acaricidal activity against spider mites. Cyflumetofen can be used in studies related to Parkinson's disease and infestations by spider mites (Tetranychus urticae, Tetranychus kanzawai, Panonychus citri)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cyflumetofen | 98.94% | Cyflumetofen is a non-systemic acylacetonitrile Acaricide. Cyflumetofen interferes with the Wnt/β-catenin signaling pathway, induces Apoptosis, and reduces the level of tight junction proteins. Cyflumetofen upregulates the expression of Pink1, Parkin and Lrrk2 genes associated with the pathogenesis of Parkinson's disease in zebrafish larvae. Cyflumetofen induces developmental toxicity and oxidative stress in zebrafish larvae, damages neurons, reduces motor activity, alters brain tissue structure, and disrupts blood-brain barrier structure. Cyflumetofen exhibits acaricidal activity against spider mites. Cyflumetofen can be used in studies related to Parkinson's disease and infestations by spider mites (Tetranychus urticae, Tetranychus kanzawai, Panonychus citri). | ||||||||||||||||||||
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Cyflumetofen (Standard) | ≥98% | Cyflumetofen (Standard) is the analytical standard of Cyflumetofen (HY-W663938). This product is intended for research and analytical applications. Cyflumetofen is a non-systemic acylacetonitrile Acaricide. Cyflumetofen interferes with the Wnt/β-catenin signaling pathway, induces Apoptosis, and reduces the level of tight junction proteins. Cyflumetofen upregulates the expression of Pink1, Parkin and Lrrk2 genes associated with the pathogenesis of Parkinson's disease in zebrafish larvae. Cyflumetofen induces developmental toxicity and oxidative stress in zebrafish larvae, damages neurons, reduces motor activity, alters brain tissue structure, and disrupts blood-brain barrier structure. Cyflumetofen exhibits acaricidal activity against spider mites. Cyflumetofen can be used in studies related to Parkinson's disease and infestations by spider mites (Tetranychus urticae, Tetranychus kanzawai, Panonychus citri). | ||||||||||||||||||||
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- [1]. Wang WG, et al. Cyflumetofen disrupts the blood-brain barrier and induces neurotoxicity in zebrafish larvae. Chemico-biological interactions. 2026 Mar 01;426:111911. [Content Brief]
- [2]. Hayashi N, et al. Cyflumetofen, a novel acaricide - its mode of action and selectivity. Pest management science. 2013 Sep;69(9):1080-4. [Content Brief]
Keywords
