Cyflumetofen (Standard)
Cyflumetofen (Standard) is the analytical standard of Cyflumetofen (HY-W663938). This product is intended for research and analytical applications. Cyflumetofen is a non-systemic acylacetonitrile Acaricide. Cyflumetofen interferes with the Wnt/β-catenin signaling pathway, induces Apoptosis, and reduces the level of tight junction proteins. Cyflumetofen upregulates the expression of Pink1, Parkin and Lrrk2 genes associated with the pathogenesis of Parkinson's disease in zebrafish larvae. Cyflumetofen induces developmental toxicity and oxidative stress in zebrafish larvae, damages neurons, reduces motor activity, alters brain tissue structure, and disrupts blood-brain barrier structure. Cyflumetofen exhibits acaricidal activity against spider mites. Cyflumetofen can be used in studies related to Parkinson's disease and infestations by spider mites (Tetranychus urticae, Tetranychus kanzawai, Panonychus citri).
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 400882-07-7
- Formula: C24H24F3NO4
- Molecular Weight:447.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 400882-07-7
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Molecular Weight 447.45
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Formula C24H24F3NO4
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SMILES
COCCOC(C(C(C1=C(C(F)(F)F)C=CC=C1)=O)(C2=CC=C(C(C)(C)C)C=C2)C#N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang WG, et al. Cyflumetofen disrupts the blood-brain barrier and induces neurotoxicity in zebrafish larvae. Chemico-biological interactions. 2026 Mar 01;426:111911. [Content Brief]
[2]. Hayashi N, et al. Cyflumetofen, a novel acaricide - its mode of action and selectivity. Pest management science. 2013 Sep;69(9):1080-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Cyflumetofen (Standard)
- 400882-07-7
- Reference Standards
- Parasite
- Wnt
- β-catenin
- Apoptosis
- PINK1/Parkin
- LRRK2
- Apis mellifera
- Panonychus citri
- Parkinson's disease
- Tetranychus kanzawai
- mitochondria complex II
- Wnt/β-catenin signaling pathway
- zebrafish larvae
- Tetranychus urticae
- Mus musculus
- Rattus norvegicus
- Inhibitor
- inhibitor
- inhibit