40254-90-8
40254-90-8
Chemical Structure
NSC693868
- CAS No.: 40254-90-8
- Formula:C9H7N5
- Molecular Weight:185.19
IUPAC Name: 1H-pyrazolo[3,4-b]quinoxalin-3-amine
InChIKey: DWHVZCLBMTZRQM-UHFFFAOYSA-N
SMILES: NC1=NNC2=NC3=CC=CC=C3N=C21
Biological Activity: NSC693868 is a selective inhibitor of CDK1 and CDK5 with IC50s of 600 nM and 400 nM, respectively. NSC693868 less potently inhibits GSK3β with an IC50 of 1 µM) and does not block CDC25 activity. NSC693868 is used to help define the roles of CDK1 and CDK5 in various signaling pathways[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NSC693868 | 99.0% | NSC693868 is a selective inhibitor of CDK1 and CDK5 with IC50s of 600 nM and 400 nM, respectively. NSC693868 less potently inhibits GSK3β with an IC50 of 1 µM) and does not block CDC25 activity. NSC693868 is used to help define the roles of CDK1 and CDK5 in various signaling pathways. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-100044SR 4330 -
Similarity Score 0.66
HY-W0686821-Hydroxyphenazine -
Similarity Score 0.65
HY-W016477Phenazine -
Similarity Score 0.64
HY-208032,3-Dihydroxyquinoxaline -
Similarity Score 0.62
HY-121559Strinoline -
Similarity Score 0.61
HY-114652AalphaC -
Similarity Score 0.61
HY-W700491AalphaC-15N3 -
Similarity Score 0.61
HY-W0156722-Methylquinoxaline -
Similarity Score 0.61
HY-B1422R9-Aminoacridine (Standard) -
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