1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. SR 4330

SR 4330  (Synonyms: 1,2,4-Benzotriazin-3-amine; Win 60109)

Cat. No.: HY-100044
Handling Instructions Technical Support

SR 4330 is a cytotoxic compound that targets hypoxic cells. The lower limits of quantification are 40 ng/mL and 20 ng/mL in mouse and human plasma.

For research use only. We do not sell to patients.

SR 4330

SR 4330 Chemical Structure

CAS No. : 20028-80-2

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Description

SR 4330 is a cytotoxic compound that targets hypoxic cells. The lower limits of quantification are 40 ng/mL and 20 ng/mL in mouse and human plasma[1].

Molecular Weight

146.15

Formula

C7H6N4

CAS No.
Appearance

Solid

Color

Brown to dark brown

SMILES

NC1=NC2=CC=CC=C2N=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (855.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8423 mL 34.2114 mL 68.4229 mL
5 mM 1.3685 mL 6.8423 mL 13.6846 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.8423 mL 34.2114 mL 68.4229 mL 171.0571 mL
5 mM 1.3685 mL 6.8423 mL 13.6846 mL 34.2114 mL
10 mM 0.6842 mL 3.4211 mL 6.8423 mL 17.1057 mL
15 mM 0.4562 mL 2.2808 mL 4.5615 mL 11.4038 mL
20 mM 0.3421 mL 1.7106 mL 3.4211 mL 8.5529 mL
25 mM 0.2737 mL 1.3685 mL 2.7369 mL 6.8423 mL
30 mM 0.2281 mL 1.1404 mL 2.2808 mL 5.7019 mL
40 mM 0.1711 mL 0.8553 mL 1.7106 mL 4.2764 mL
50 mM 0.1368 mL 0.6842 mL 1.3685 mL 3.4211 mL
60 mM 0.1140 mL 0.5702 mL 1.1404 mL 2.8510 mL
80 mM 0.0855 mL 0.4276 mL 0.8553 mL 2.1382 mL
100 mM 0.0684 mL 0.3421 mL 0.6842 mL 1.7106 mL
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SR 4330 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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