438196-25-9
438196-25-9
Chemical Structure
Amb929
Synonym(s): ZINC000002782982
- CAS No.: 438196-25-9
- Formula:C29H27N3O4S
- Molecular Weight:513.61
SMILES: CC(C)COC1=CC(C2=NC3=CC=CC=C3C(C(NC(NC4=CC=C(C(OC)=O)C=C4)=S)=O)=C2)=CC=C1
Biological Activity: Amb929 (ZINC000002782982), a nsp3 ligand, is an anti-SARS-CoV-2 agent. Amb929 inhibits SARS-CoV2-mNG replication in VeroE6 cells with an EC50 of 34.7 µM. Amb929 has limited and moderate cytotoxicity for VeroE6 cells (CC50: 281 µM). Amb929 also inhibits SARS-CoV-2-mNG replication in Human Airway Epithelium (HAE)[1].
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Amb929 | Amb929 (ZINC000002782982), a nsp3 ligand, is an anti-SARS-CoV-2 agent. Amb929 inhibits SARS-CoV2-mNG replication in VeroE6 cells with an EC50 of 34.7 µM. Amb929 has limited and moderate cytotoxicity for VeroE6 cells (CC50: 281 µM). Amb929 also inhibits SARS-CoV-2-mNG replication in Human Airway Epithelium (HAE). | |||||||||||||||||||||
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References
Keywords
