452967-14-5
452967-14-5
Chemical Structure
IR415
- CAS No.: 452967-14-5
- Formula:C13H14F2N4S
- Molecular Weight:296.34
IUPAC Name: 1-(3-(1H-imidazol-1-yl)propyl)-3-(2,4-difluorophenyl)thiourea
InChIKey: KRSBPLFMLHNMPU-UHFFFAOYSA-N
SMILES: S=C(NCCCN1C=CN=C1)NC2=CC=C(F)C=C2F
Biological Activity: IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity. IR415 selectively interacts with HBx (Kd=2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease[1]. HBx: hepatitis B virus X protein.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IR415 | 98.11% | IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity. IR415 selectively interacts with HBx (Kd=2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. HBx: hepatitis B virus X protein. | ||||||||||||||||||||
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References
Keywords
