4611-02-3
4611-02-3
Chemical Structure
Chlorproethazine hydrochloride
- CAS No.: 4611-02-3
- Formula:C19H24Cl2N2S
- Molecular Weight:383.38
IUPAC Name: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-diethylpropan-1-amine hydrochloride
InChIKey: XXQMDKCWUYZXOF-UHFFFAOYSA-N
SMILES: CCN(CC)CCCN1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13.Cl
Biological Activity: Chlorproethazine hydrochloride is an orally active phenothiazine compound. Chlorproethazine hydrochloride can eliminate spasticity when administered intravenously and also effectively reduce rigidity in decerebrate cats. Chlorproethazine hydrochloride can be used in the research of neurological diseases[1][2][3].
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Chlorproethazine hydrochloride | Chlorproethazine hydrochloride is an orally active phenothiazine compound. Chlorproethazine hydrochloride can eliminate spasticity when administered intravenously and also effectively reduce rigidity in decerebrate cats. Chlorproethazine hydrochloride can be used in the research of neurological diseases. | |||||||||||||||||||||
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Chlorproethazine-d10 hydrochloride | Chlorproethazine-d10 hydrochloride is the deuterium labeled Chlorproethazine hydrochloride. | |||||||||||||||||||||
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References
- [1]. Matthews WB. The action of chlorproethazine on spasticity. Brain. 1965 Dec;88(5):1057-64. [Content Brief]
- [2]. Barbaud A, et al. Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines. Contact Dermatitis. 2001 Jun;44(6):373. [Content Brief]
- [3]. Keary EM, et al. A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions. Br J Pharmacol Chemother. 1967 Jun;30(2):400-16. [Content Brief]
