479413-70-2
479413-70-2
Chemical Structure
AUDA
- CAS No.: 479413-70-2
- Formula:C23H40N2O3
- Molecular Weight:392.58
IUPAC Name: 12-(3-(adamantan-1-yl)ureido)dodecanoic acid
InChIKey: XLGSEOAVLVTJDH-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCCCCCCCNC(NC1(C2)CC3CC2CC(C3)C1)=O
Biological Activity: AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively[1]. AUDA has anti-inflammatory activity[2].
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AUDA | 98.0% | AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively. AUDA has anti-inflammatory activity. | ||||||||||||||||||||
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AUDA (Standard) | ≥98% | AUDA (Standard) is the analytical standard of AUDA. This product is intended for research and analytical applications. AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively. AUDA has anti-inflammatory activity. | ||||||||||||||||||||
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References
- [1]. Morisseau C, et al. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases.Biochem Pharmacol. 2002 May 1;63(9):1599-608. [Content Brief]
- [2]. Kim HS, et al. Differential Effects of sEH Inhibitors on the Proliferation and Migration of Vascular Smooth Muscle Cells.Int J Mol Sci. 2017 Dec 11;18(12). [Content Brief]
