489415-96-5
489415-96-5
Chemical Structure
SBC-115076
- CAS. Nr.: 489415-96-5
- Formula:C31H33N3O5
- Molecular Weight:527.61
IUPAC Name: 4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1,5-dihydro-2H-pyrrol-2-one
InChIKey: UNINQWCCZAGYSH-UHFFFAOYSA-N
SMILES: O=C1N(CCCN2CCOCC2)C(C3=CC=NC=C3)C(C(C4=CC=C(OCC5=CC=CC=C5)C(C)=C4)=O)=C1O
Biological Activity: SBC-115076 is a potent proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PCSK9 is a proprotein convertase, which plays a crucial role in LDL receptor metabolism[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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SBC-115076 | 99.28% | SBC-115076 is a potent proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PCSK9 is a proprotein convertase, which plays a crucial role in LDL receptor metabolism. | ||||||||||||||||||||
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References
- [1]. Chanisa Thonusin, et al. The comparative effects of high dose atorvastatin and proprotein convertase subtilisin/kexin type 9 inhibitor on the mitochondria of oxidative muscle fibers in obese-insulin resistant female rats. Toxicol Appl Pharmacol. 2019 Nov 1;382:114741. [Content Brief]
- [2]. Wiciński M, et al. PCSK9 signaling pathways and their potential importance in clinical practice. EPMA J. 2017;8(4):391-402. Published 2017 Aug 14. [Content Brief]
Keywords
