Hsp90-IN-38
Hsp90-IN-38 (compound 20m) is a HSP90 (heat shock protein) inhibitor. Hsp90-IN-38 exhibits strong HSP90 binding affinity with a Kd of 87 nM. Hsp90-IN-38 inhibits ATPase with an IC50 of 0.13 μM. Hsp90-IN-38 inhibits HCT116, MCF-7, SKBr3, K562 and A549 cells with IC50s of 0.187, 0.072, 0.105, 0.403 and 031 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 3065556-04-6
- Formula: C28H35N3O5
- Molecular Weight:493.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HSP90 68 nM (Kd) |
Chemical Information
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CAS No. 3065556-04-6
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Molecular Weight 493.59
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Formula C28H35N3O5
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SMILES
O=C([C@@H]1N(C(C2=CC(C3CC3)=C(O)C=C2O)=O)C[C@@H](C4=CC=CC=C4)C1)NCCCN5CCOCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)