49686-57-9
49686-57-9
Chemical Structure
Drupacine
- CAS No.: 49686-57-9
- Formula:C18H21NO5
- Molecular Weight:331.36
IUPAC Name: (6R,11bS,12S,13R,14aS)-13-methoxy-2,3,5,6,11b,12,13,14-octahydro-1H-6,13-epoxy[1,3]dioxolo[4',5':4,5]benzo[1,2-d]cyclopenta[b]pyrrolo[1,2-a]azepin-12-ol
InChIKey: KYTDBKDWDOVRLJ-FLXSYLCISA-N
SMILES: O[C@H]1[C@]2([H])[C@]34C[C@]1(O[C@](CN3CCC4)([H])C5=CC(OCO6)=C6C=C25)OC
Biological Activity: Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity[1][2].
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Drupacine | Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity. | |||||||||||||||||||||
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References
- [1]. Li Y, et al. Preparation of Stereo-Divergent Compounds from the Natural Product Drupacine Based on Complexity-to-Diversity Strategy. Chem Biodivers. 2023 Jun;20(6):e202300263. [Content Brief]
- [2]. Wen Y, et al. Nematotoxicity of drupacine and a Cephalotaxus alkaloid preparation against the plant-parasitic nematodes Meloidogyne incognita and Bursaphelenchus xylophilus. Pest Manag Sci. 2013 Sep;69(9):1026-33. [Content Brief]
Keywords
