501017-82-9
Chemical Structure
IMB-881
- CAS No.: 501017-82-9
- Formula:C19H17ClN2O
- Molecular Weight:324.80
InChIKey: ZYGKVGCVMPUZOC-UHFFFAOYSA-N
SMILES: ClC(C1=CC=CN=C12)=CC3=C2OCN(CCC4=CC=CC=C4)C3
Biological Activity: IMB-881 is an antibacterial agent. IMB-881 binds to LptA to inhibit the interaction between LptA and LptC. IMB-881 shows potent antibacterial activity against Gram-negative bacteria[1][2].
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IMB-881 | 90% | IMB-881 is an antibacterial agent. IMB-881 binds to LptA to inhibit the interaction between LptA and LptC. IMB-881 shows potent antibacterial activity against Gram-negative bacteria. | ||||||||||||||||||||
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- [1]. Liu C, et al. Synthesis, biological evaluation and validation of IMB-881 derivatives as anti-Gram-negative bacterial agents. Bioorg Med Chem. 2025 Mar 1;119:118066. [Content Brief]
- [2]. Zhang X, et al. Identification of an anti-Gram-negative bacteria agent disrupting the interaction between lipopolysaccharide transporters LptA and LptC. Int J Antimicrob Agents. 2019 Apr;53(4):442-448. [Content Brief]
Keywords