501693-48-7
501693-48-7
Chemical Structure
TIE-2/VEGFR-2 kinase-IN-2
- CAS. Nr.: 501693-48-7
- Formula:C20H13F4N5O2
- Molecular Weight:431.34
IUPAC Name: 1-(4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
InChIKey: KNDPXYAMINMLED-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC(C=C2)=CC=C2C3=COC4=C3C(N)=NC=N4
Biological Activity: TIE-2/VEGFR-2 kinase-IN-2 is a potent dual VEGFR2 and Tie-2 inhibitor with pIC50 values of 8.61 and 8.56, respectively[1]. TIE-2/VEGFR-2 kinase-IN-2 is an anti-angiogenic agent and can be used for cancer research[2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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TIE-2/VEGFR-2 kinase-IN-2 | 99.81% | TIE-2/VEGFR-2 kinase-IN-2 is a potent dual VEGFR2 and Tie-2 inhibitor with pIC50 values of 8.61 and 8.56, respectively. TIE-2/VEGFR-2 kinase-IN-2 is an anti-angiogenic agent and can be used for cancer research. | ||||||||||||||||||||
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References
Keywords
