50468-56-9
Chemical Structure
Epilactose
- CAS No.: 50468-56-9
- Formula:C12H22O11
- Molecular Weight:342.30
IUPAC Name: 4,9-dibromo-2-(2-ethylhexyl)-7-(2-octyldodecyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone
InChIKey: DKXNBNKWCZZMJT-QMRWEYQWSA-N
SMILES: O=C[C@@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)CO
Biological Activity: Epilactose is an orally active prebiotic disaccharide. Epilactose resists gastrointestinal digestion, stimulates the intestinal epithelium, and induces myosin regulatory light chain phosphorylation, activating the perijunctional actin-myosin ring and paracellular transport. Epilactose produces short-chain fatty acids and organic acids through cecal microbial fermentation, induces paracellular calcium and iron absorption, lowers cecal pH, and increases cecal calcium and magnesium solubility. Epilactose inhibits hepatic cholesterol synthesis. Epilactose can be used for research on osteopenia, colon cancer, Crohn's disease, post-gastrectomy osteopenia and anemia, and obesity[1][2][3][4][5][6][7].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Epilactose | 99.89% | Epilactose is an orally active prebiotic disaccharide. Epilactose resists gastrointestinal digestion, stimulates the intestinal epithelium, and induces myosin regulatory light chain phosphorylation, activating the perijunctional actin-myosin ring and paracellular transport. Epilactose produces short-chain fatty acids and organic acids through cecal microbial fermentation, induces paracellular calcium and iron absorption, lowers cecal pH, and increases cecal calcium and magnesium solubility. Epilactose inhibits hepatic cholesterol synthesis. Epilactose can be used for research on osteopenia, colon cancer, Crohn's disease, post-gastrectomy osteopenia and anemia, and obesity. | ||||||||||||||||||||
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4-O-β-D-Galactopyranosyl-D-mannose-13C | 4-O-β-D-Galactopyranosyl-D-mannose-13C is the 13C labeled 4-O-β-D-Galactopyranosyl-D-mannose. | |||||||||||||||||||||
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References
- [1]. Suzuki T, et al. The nondigestible disaccharide epilactose increases paracellular Ca absorption via rho-associated kinase- and myosin light chain kinase-dependent mechanisms in rat small intestines. Journal of agricultural and food chemistry. 2010 Feb 10;58(3):1927-32.
- [2]. Nishimukai M, et al. Effects of epilactose on calcium absorption and serum lipid metabolism in rats. Journal of agricultural and food chemistry. 2008 Nov 12;56(21):10340-5.
- [3]. Watanabe J, et al. Prebiotic properties of epilactose. Journal of dairy science. 2008 Dec;91(12):4518-26.
- [4]. Cardoso BB, et al. Epilactose as a Promising Butyrate-Promoter Prebiotic via Microbiota Modulation. Life (Basel, Switzerland). 2024 May 18;14(5):643. [Content Brief]
- [5]. Suzuki T, et al. Ingestion of epilactose, a non-digestible disaccharide, improves postgastrectomy osteopenia and anemia in rats through the promotion of intestinal calcium and iron absorption. Journal of agricultural and food chemistry. 2010 Oct 13;58(19):10787-92.
- [6]. Ito S, et al. Enzymatic properties of cellobiose 2-epimerase from Ruminococcus albus and the synthesis of rare oligosaccharides by the enzyme. Applied microbiology and biotechnology. 2008 Jun;79(3):433-41.
- [7]. Chen Z, et al. Characterization of an epilactose-producing cellobiose 2-epimerase from Clostridium sp. TW13 and reutilization of waste milk. Food chemistry. 2025 Jul 15;480:143948.
